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General mechanism of action of nerve growth factor (NGF) in the systemic immune response, neuroinflammation, regeneration, and tissue repair. NGF acts on lymphocytes, mast cells, and macrophages to induce inflammation. NGF acts on fibroblasts and keratinocytes to induce tissue repair. NGF acts on oligodendrocytes, Schwann cells, and neurons to induce repair or apoptosis.
