Table 1.

Epidemiological features and clinical findings in 284 patients with hereditary ichthyosis

Clinico-epidemiologic data	Ichthyosis vulgaris (IV) (%)	X-linked ichthyosis (XLI) (%)	Lamellar ichthyosis (LI) (%)	Congenital ichthyosiform erythroderma(CIE) (%)	Sjogren-Larsson syndrome(SLS) (%)	Total (%)
Patients, number (%)	38 (13.4)	30 (10.6)	108 (38)	76 (26.8)	32 (11.3)	284 (100)
Egyptian nationality	13.4	10.56	38	26.76	11.26	100
Sex: male	5.63	9.85	15.49	11.26	6.33	48.59
Positive parental relationship	9.15	7.39	32.39	21.83	8.09	78.87
Positive family history	10.17	7.36	31.22	18.94	3.85	71.57
Age of onset:
Onset at birth/neonatal period	–	7.4	38	26.8	2.9	75
Onset after 1 month of life (1–3 m)	13.4	3.2	–	–	8.5	25
Skin lesions:
Collodion baby or exaggerated skin desquamation and peeling at birth	–	4.2	38	26.76		69
Diffuse erythema and scaling					11.3	11.3
Generalized scales, which range from fine and white to thick, dark and plate like	–	–	15 Coarse plate-like scales	16 Fine grey white scales		31
Adherent brown scales/extensor surfaces	13.4	10.6	–	–	–	24
Preserved flexures	13.38	10.56	–	–	–	24
Dandruff	5.3	2.5	3.5	14		25.3
Palmoplantar keratoderma			6	9		15
Nail abnormalities			3.2	4.6		7.7
Atopic dermatitis	13.4					13.4
Corneal opacity		5.6				5.6
Ectropion	–	–	4.2	8.4	–	12.7
Recurrent conjunctivitis		2.5	4.2	3.2		9.9
Mental retardation/learning difficulties	–	2.8	–	3.2	11.3	17.3
Seizures/muscle spasms	–	–	–	–	11.3	11.3
Speech defect	–	–			6	6
Growth retardation/short stature	–	–	15	5	2	21.4
Eclabion			19.4	6		25.4
Alopecia	–	–	3.5	6	–	9.5