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. 2018 May 7;9:864. doi: 10.3389/fimmu.2018.00864

Table 8.

Comparison of treatment in successful and complicated pregnancy.

Treatment Adverse pregnancy outcome (n = 50) (17.7%) Successful pregnancies (n = 233) (82.3%) p-Value
LDA monotherapy (n = 67) 9/50 (18) 58/233 (24.9) NS
LMWH monotherapy (n = 5) 3/50 (6) 2/233 (0.8) 0.040*
LDA + LMWH (n = 211) 38/50 (76) 173/233 (74.2) NS
LDA + LMWH prophylactic dosage (n = 161) 28/50 (56) 133/233 (57.1) NS
LDA + LMWH therapeutic dosage (n = 50) 10/50 (20) 40/233 (17.2) NS
LDA + LMWH, start at positive pregnancy test (n = 143) 28/50 (56) 115/233 (49.3) NS
LDA + LMWH, start between 6 and 8 weeks of gestation (n = 16) 0/50 (0) 16/233 (6.8) NS
LDA + LMWH, Start between 9 and 12 weeks of gestation (n = 22) 6/50 (12) 16/233 (6.8) NS
LDA + LMWH, start after 12 weeks of gestation (n = 30) 4/50 (8) 26/233 (11.1) NS
Hydroxychloroquine (n = 32) 6/50 (12) 26/233 (11.2) NS
Steroids (n = 16) 4/50 (8) 12/233 (5.1) NS

LDA, low-dose aspirin; LMWH, low-molecular-weight heparin.

*OR 7.37; CI 95% 0.96–65.