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. 2018 May 14;24(18):1995–2008. doi: 10.3748/wjg.v24.i18.1995

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©The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.

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Probiotic supplementation does not modify the tumour microenvironment. Real-time RT-PCR analysis of TNF-α (A), IL-6 (B), IL-1β (C), IL-10 (D), TGF-β1 (E), and IL-13 (F), IL-4(G) in colon tumour tissue of control and probiotic groups; results are presented relative to those of Gapdh. H: Concentration of cytokines in the tumour tissue analysed by Bio-Plex Multiplex cytokine assay at day 60 after injection with azoxymethane. Mann-Whitney U test. Data from two independent experiments, presented as mean and standard deviation.