0 |
No pathological change |
Normal mucosa |
1 |
Focal loss of surface epithelium |
Subepithelial space at villus tips |
2 |
Mucosal infarction (extensive loss of surface epithelium, loss of variable amounts of lamina propria, sparing of basal glands, intact muscularis mucosae) |
Extension of subepithelial space with moderate lifting |
3 |
Submucosal infarction (variable necrosis of submucosa, complete mucosal necrosis, intact muscularis mucosae) |
Massive lifting down the sides of the villi, some denuded tips |
4 |
Mural infarction (loss of muscularis mucosae, complete necrosis of mucosa and submucosa) |
Denuded villi, dilated capillaries |
5 |
Mural infarction (involvement of inner layer of muscularis propria, complete necrosis of mucosa and submucosa) |
Disintegration of lamina propria |
6 |
Transmural infarction (complete necrosis of the bowel wall) |
Crypt layer injury |
7 |
|
Transmucosal infarction |
8 |
|
Transmural infarction |