Skip to main content
. 2018 May 14;24(18):2009–2023. doi: 10.3748/wjg.v24.i18.2009

Table 1.

Comparison of modified Swerdlow et al[21,27,28] and Park/Chiu et al[22,26] systems for grading of histological damage on the intestine

Grade Modified Swerdlow Park/Chiu
0 No pathological change Normal mucosa
1 Focal loss of surface epithelium Subepithelial space at villus tips
2 Mucosal infarction (extensive loss of surface epithelium, loss of variable amounts of lamina propria, sparing of basal glands, intact muscularis mucosae) Extension of subepithelial space with moderate lifting
3 Submucosal infarction (variable necrosis of submucosa, complete mucosal necrosis, intact muscularis mucosae) Massive lifting down the sides of the villi, some denuded tips
4 Mural infarction (loss of muscularis mucosae, complete necrosis of mucosa and submucosa) Denuded villi, dilated capillaries
5 Mural infarction (involvement of inner layer of muscularis propria, complete necrosis of mucosa and submucosa) Disintegration of lamina propria
6 Transmural infarction (complete necrosis of the bowel wall) Crypt layer injury
7 Transmucosal infarction
8 Transmural infarction