Table 2. Off-Target Panel of Compounds 5, 16, and 21.
| IC50 (μM) |
|||
|---|---|---|---|
| off-target assay | 5 | 16 | 21 |
| α-adrenergic 2A | 3.7 | >30 | 5.9 |
| μ-opioid | 14.9 | >30 | 11.3 |
| nAChR α1 | >30 | >30 | 11.3 |
| acetylcholine esterase | >30 | >30 | 10.7 |
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