Table 3. Physicochemical Properties of Selected Compounds.

compd	pEC50	clogPa	LE	LLE
14	6.21	1.27	0.37	4.94
15	6.42	1.58	0.36	4.84
16	6.36	2.78	0.30	3.58
18	6.29	1.98	0.31	4.31
42	6.06	2.23	0.29	3.83
44	6.06	2.73	0.28	3.33
46	6.06	2.19	0.28	3.87
48	6.28	3.02	0.29	3.26
49	6.50	2.93	0.28	3.57
50	6.46	2.04	0.29	4.42
51	6.21	2.45	0.28	3.76
52	6.35	2.45	0.29	3.90
53	6.88	2.21	0.30	4.67
54	6.07	2.29	0.26	3.78
56	7.23	2.36	0.31	4.87
57	6.08	2.01	0.24	4.07
58	6.52	2.36	0.28	4.16
59	6.70	1.64	0.29	5.06
60	6.19	1.31	0.28	4.88
63	7.38	2.15	0.32	5.23

^aCalculated by the Chembiodraw Ultra 11.0.