Table 2. Antibacterial Activities of the Target Compounds against Drug-Resistant Gram-Positive Strains.
| MIC
(μg/mL)a |
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| MRSA |
VISA |
|||||||||
| Code | ATCC 33591 | 13–18 | 13–23 | 12–3 | 12–8 | 12–13 | 12–16 | ATCC-BAA-1708b | ATCC 700698 | ATCC 700699 |
| 2 | 4 | 1 | 2 | 4 | 8 | 4 | 2 | 8 | 16 | 32 |
| 4 | 0.25 | 0.25 | 0.25 | 0.25 | 0.5 | 1 | 0.5 | 0.5 | 0.5 | 0.25 |
| 5a | >64 | >64 | >64 | >64 | >64 | >64 | >64 | >64 | >64 | >64 |
| 5b | 32 | 32 | 32 | 32 | 64 | 32 | 32 | 32 | >64 | >64 |
| 5c | >64 | >64 | >64 | >64 | >64 | >64 | >64 | >64 | >64 | >64 |
| 5d | 2 | 4 | 2 | 4 | 4 | 4 | 2 | 4 | 8 | 8 |
| 5e | 16 | 32 | 16 | 16 | 16 | 32 | 32 | 32 | >64 | >64 |
| 5f | 8 | 16 | 8 | 8 | 8 | 8 | 16 | 64 | >64 | >64 |
| 5g | >64 | >64 | >64 | >64 | >64 | >64 | >64 | >64 | >64 | >64 |
| 5h | 8 | 8 | 8 | 16 | 8 | 4 | 4 | 32 | >64 | >64 |
| 5i | 16 | 16 | 16 | 16 | 8 | 32 | 16 | 64 | >64 | >64 |
| 5j | 4 | 8 | 4 | 4 | 8 | 4 | 8 | 16 | >64 | >64 |
| 5k | 4 | 4 | 16 | 16 | 16 | 8 | 8 | 64 | >64 | >64 |
| 5l | 4 | 4 | 4 | 4 | 8 | 4 | 4 | 8 | >64 | >64 |
| 6a | 64 | 64 | 64 | 64 | 64 | 64 | 64 | 64 | 32 | >64 |
| 6b | 32 | 32 | 32 | 32 | 32 | 32 | 32 | 64 | 16 | >64 |
| 6c | 64 | 64 | 64 | 32 | 64 | 32 | 64 | >64 | >64 | >64 |
| 7 | 8 | 8 | 8 | 8 | 8 | 8 | 8 | 16 | 4 | 8 |
| 8 | 4 | 8 | 8 | 8 | 4 | 4 | 4 | 4 | 64 | 4 |
| 9a | >64 | >64 | >64 | >64 | >64 | >64 | >64 | >64 | >64 | >64 |
| 9b | 8 | 8 | 8 | 8 | 8 | 16 | 8 | 4 | 64 | 4 |
| 9c | >64 | >64 | >64 | >64 | >64 | >64 | >64 | >64 | >64 | >64 |
| 9d | 64 | 32 | 8 | 32 | 32 | 16 | 16 | 16 | >64 | 4 |
| 9e | 2 | 2 | 2 | 2 | 2 | 4 | 2 | 2 | 16 | 8 |
| 9f | >64 | >64 | >64 | >64 | >64 | >64 | >64 | >64 | >64 | >64 |
| Lev | 0.125 | 32 | 32 | 32 | 32 | 32 | 32 | 16 | 32 | 2 |
a
MIC (μg/mL), minimum inhibitory concentration.
b
mupA positive (isolates with mupirocin resistance).