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. 2018 Apr 20;9(5):502–506. doi: 10.1021/acsmedchemlett.8b00125

Table 2. Antiproliferation Activities for 26 in Hematological Tumor Cell Linesa.

IC50 (nM) 1 2 3 4 5 6 SAHA lenalidomide CC-885
MV-4–11 28.3 24.5 27.2 66.3 29.3 29.6 NA >20000 0.3
MM-1S 21.0 12.0 143.0 24.0 28.0 25.0 2844 NA NA
a

MTS assay. The data are the mean of triplicate determinations. NA: not available. MV-4–11: human myeloid leukemia cell lines. MM-1S: human myeloma cell lines.