Table 3. meta-Olefination of phenylethylamine derivatives ^a .

^aReaction conditions: 3 (0.2 mmol), ethyl acrylate (0.4 mmol), Pd(OAc)₂ (10 mol%), Ac-Gly-OH (20 mol%), AgOAc (0.6 mmol), DCE (1 mL), HFIP (1 mL), 24–48 h, 80 °C, N₂. Isolated yields are reported, see the ESI† for details.

^b90 °C.

^cDMF (1 mmol) was added.

^dDCE (0 mL)/HFIP (2 mL).

^eAround 10% of other isomers detected by ¹H NMR.