Table 3.
Comparison of different management approach groups.
| Variable | All patients n = 350 | LC-IOC-first n = 118 | ERCP-first n = 232 | p value |
|---|---|---|---|---|
| Patient characteristics | ||||
| Age (year), mean (SD) | 65.2 (17.9) | 64.9 (17.4) | 65.4 (18.2) | 0.777 |
| Female; n (%) | 222 (63.4) | 76 (64.4) | 146 (62.9) | 0.786 |
| ASA grade | 0.429 | |||
| I–II | 165 (47.2) | 45 (38.5) | 12 (52.2) | |
| III–IV | 185 (52.8) | 73 (61.5) | 11 (47.8) | |
| Preoperative diagnosis | ||||
| Choledocholithiasis (CBDS on US/CT) | 133 (38) | 5 (4.5) | 128 (55.2) | 0.000 |
| Acute cholecystitis, n (%) | 101 (28.9) | 45 (38.1) | 56 (24.1) | 0.006 |
| Ascending cholangitis, n (%) | 56 (16) | 9 (7.7) | 47 (20.5) | 0.002 |
| Acute biliary pancreatitis, n (%) | 63 (18) | 25 (21.1) | 38 (16.4) | 0.268 |
| Predictors | ||||
| Preoperative bilirubin (µmol/l), mean (SD) | 74.8 (63.3) | 50.9 (47.9) | 86.9 (66.7) | 0.000 |
| Dilated CBDS on US >6 mm, n (%) | 293 (83.7) | 70 (59.3) | 223 (96.1) | 0.000 |
| CBD diameter (mm), mean (SD) | 10.17 (4.2) | 6.88 (2.3) | 11.8 (3.9) | 0.000 |
| VUHI ≥ 4.7, n (%) | 239 (68.3) | 34 (28.8) | 205 (88.4) | 0.000 |
| Outcomes | ||||
| CBDS detected, n (%) | 226 (64.6) | 35 (29.7) | 191 (82.3) | 0.000 |
| CBD pathology (stones + strictures), n (%) | 240 (68.6) | 35 (29.7) | 205 (88.4) | 0.000 |
| Duration from intervention to end of hospital treatment | 6.89 (8.62) | 4.67 (5.78) | 8.03 (9.57) | 0.000 |
LC-IOC: laparoscopic cholecystectomy with intraoperative cholangiography; ERCP: endoscopic retrograde cholangiopancreatography; ASA: American Society of Anesthesiologists; VUHI: Vilnius University Hospital Index; CBDS: common bile duct stones; US: ultrasound; CT: computed tomography; CI: confidence interval; SD: standard deviation. Statistically significant values are typed in bold.