Table 4.
Distribution of genotypes of the SNP rs3775292 (TLR3) and rs10062929 (TSLP) and dominant and recessive models.
Dominant model |
Recessive model |
|||||
---|---|---|---|---|---|---|
Controls | EoE patients | p | OR (95% CI) | p | OR (95% CI) | |
TLR3_rs3775292 | ||||||
CC | 28 | 9 | 0.0042 | 0.60 (0.42–0.85) | 0.09 | 0.52 (0.22–1.10) |
CG | 144 | 67 | ||||
GG | 193 | 142 | ||||
TSLP_rs10062929 | ||||||
AA | 6 | 2 | 1.1E-6 | 0.23 (0.11–0.44) | 0.36 | 0.36 (0.01–2.46) |
AC | 78 | 13 | ||||
CC | 276 | 203 |
Model dominant: CC+CG vs GG (TLR3) and AA+AC vs CC (TSLP).
Model recessive: CC vs CG+GG (TRL3) and AA vs AC+CC (TSLP).
SNP: single-nucleotide polymorphism; EoE: eosinophilic esophagitis; TLR3: Toll-like receptor 3; TSLP: thymic stromal lymphopoietin; OR (95% CI): odds ratio with 95% confidence interval.