Table 7.

Minor allele frequencies of the SNPs studied in the TLR3 gene in EoE patients.

TLR3 SNP	MA	Aeroallergens		p	p c	OR (95% CI)	Food allergy		p	p c	OR (95% CI)
		Negatives (n = 54)	Positives (n = 164)				Negatives (n = 84)	Positives (n = 134)
rs5743303	T	0.255	0.199	0.2521	NS		0.285	0.175	0.014	0.048	0.53 (0.32–0.88)
rs5743305	A	0.362	0.351	0.8575	NS		0.331	0.367	0.4906	NS
rs11721827	C	0.011	0.094	0.0071	0.0255	9.67 (1.29–72.28)	0.038	0.092	0.0603	NS
rs7657186	A	0.196	0.204	0.8569	NS		0.190	0.208	0.6861	NS
rs13126816	A	0.315	0.303	0.8297	NS		0.294	0.314	0.698	NS
rs7668666	A	0.277	0.268	0.873	NS		0.308	0.250	0.2329	NS
rs3775292	C	0.234	0.196	0.4262	NS		0.223	0.196	0.5358	NS
rs3775291	T	0.394	0.326	0.2337	NS		0.346	0.342	0.9308	NS

SNPs: single-nucleotide polymorphisms; TLR3: Toll-like receptor 3; EoE: eosinophilic esophagitis; MA: minor allele; OR (95%CI): odds ratio with 95% confidence interval; NS: not significant p > 0.05.

p_c: corrected p value, 10,000-fold permutation testing.