Table 2.
Multivariate analysis for prediction of hepatocellular carcinoma (logistic binary regression) – entire study cohort.
| Predictive factors | Regression coefficient | OR | 95% CI | p Value | |
|---|---|---|---|---|---|
| TIPS | −1.052 | 0.35 | 0.163–0.746 | 0.001 | |
| Gender | 1.018 | 2.77 | 1.592–4.809 | <0.0001 | |
| Age | 0.047 | 1.05 | 1.028–1.069 | <0.0001 | |
| Alcohol | 1.173 | 3.23 | 1.562–6.689 | 0.002 | |
| NASH | 0.913 | 2.492 | 1.101–5.640 | 0.028 | |
| Viral hepatitis | 1.910 | 6.753 | 3.304–13.803 | <0.0001 | |
| Cholestatic liver disease | −0.334 | 0.72 | 0.289–1.772 | 0.470 | |
| Haemochromatosis | 0.823 | 2.28 | 0.905–5.731 | 0.081 | |
| MELD | −0.051 | 0.95 | 0.910–0.992 | 0.021 | |
| Constant | −6.73 |
CI: confidence interval; OR: odds ratio; MELD: model of liver end-stage disease; NASH: non-alcoholic steatohepatitis; TIPS: transjugular portosystemic shunt.
Cholestatic liver disease includes primary biliary cholangitis, primary sclerosing cholangitis and secondary sclerosing cholangitis; viral hepatitis includes chronic hepatitis C and chronic hepatitis B.