Table 3.
Structural statistics for BRD3-ET complexes with CHD4 and BRG1
| BRD3·CHD4 | BRD3·BRG1 | |
|---|---|---|
| NOE-based distance restraints | ||
| Total | 1324 | 873 |
| Intraresidue (i, i) | 337 | 248 |
| Sequential (i, i + 1) | 359 | 253 |
| Medium-range (2 ≤ |i − j| ≤4) | 352 | 196 |
| Long-range (|i − j| >4) | 276 | 176 |
| Total dihedral restraints | 136 | 144 |
| Root mean square deviation from lowest energy structurea | ||
| All backbone atoms (N, Cα, C′) (Å) | 0.8 | 1.0 |
| All heavy atoms (N, C, O, S) (Å) | 1.5 | 1.5 |
| PROCHECK Ramachandran statistics | ||
| Residues in most favored regions (%) | 95.5 | 91.7 |
| Residues in additionally allowed regions (%) | 4.1 | 7.2 |
| Residues in generously allowed regions (%) | 0.3 | 0.9 |
| Residues in disallowed regions (%) | 0.2 | 0.2 |
| Deviations from idealized geometry | ||
| Bond lengths (Å) | 0.014 | 0.015 |
| Bond angles (°) | 1.3 | 1.6 |
a Deviations are over residues 295–298 and 570–637.