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. 2018 Mar 9;293(19):7476–7485. doi: 10.1074/jbc.RA118.002233

Figure 5.

Figure 5.

TRIM24 SUMOylation regulates adhesion of MCF7 cells to ECM proteins. A, cell adhesion assay. MCF7 shCtrl, shTRIM24, shTRIM24-WT, and shTRIM24-DM cells were allowed to attach to wells coated with the indicated ECM proteins and BSA control. Following the wash step, adherent cells were stained. B, following extraction of stained cells in extraction buffer, optical density was determined and plotted as a measure of cell adhesion. Quantification from biological replicates (n = 2 for shCtrl and shTRIM24 and n = 3 for shTRIM24-WT and shTRIM24-DM). *, p < 0.05; **, p < 0.005. Error bars, S.D.