Table IV.
Enriched Kyoto Encyclopedia of Genes and Genomes pathways of four modules.
| Pathway term | P-value | Nodes |
|---|---|---|
| Module 1 | ||
| Chemokine signaling pathway | 1.14×10−10 | CXCL1, CCR7, PPBP, IL8, GNAI1, CXCR4, CXCL3, CXCL2, CXCL9, CCL19, CCL5, CXCL12 |
| Cytokine-cytokine receptor interaction | 7.02×10-8 | CXCL1, CCR7, PPBP, IL8, CXCR4, CXCL3, CXCL2, CXCL9, CCL19, CCL5, CXCL12 |
| Neuroactive ligand-receptor interaction | 7.93×10−7 | APLNR, HTR1B, SSTR2, C5AR1, S1PR1, P2RY14, ADRA2A, MTNR1B, LPAR1, HTR1D |
| Module 2 | ||
| Allograft rejection | 0.0418 | HLA-A, HLA-C |
| Graft-versus-host disease | 0.0452 | HLA-A, HLA-C |
| Type I diabetes mellitus | 0.0486 | HLA-A, HLA-C |
| Module 3 | ||
| No record | – | – |
| Module 4 | ||
| Complement and coagulation cascades | 0.0012 | VWF, A2M, F13A1, SERPINE1 |
| Calcium signaling pathway | 0.0018 | AGTR1, EDNRB, GNAQ, PTGFR, HTR2A |
| Renal cell carcinoma | 0.0198 | VEGFC, TGFB3, PIK3R1 |