Figure 2.

In order to explore the potential functions of dysregulated lncRNAs in cisplatin-resistant ovarian cancer, GO and pathway analysis were performed. (A) The GO analysis data demonstrated that gene products were primarily located on the membrane-bound organelles, extracellular regions, intracellular membrane-bound organelles, cytoplasm, intracellular and intracellular region. (B) Genes were predicted to be enriched in the following biological processes: Regulation of the mitotic cell cycle, cell division, M phase of the mitotic cycle, regulation of the cell cycle process and regulation of the cell cycle. (C) The molecular functions of these genes, including organic cyclic compound binding, protein binding, binding and ion binding. (D) Pathway analysis demonstrated that gene products were involved in several signaling pathways in humans. GO, gene ontology; DE, differently expressed; MF, molecular function; MAPK, mitogen-activated protein kinase; lncRNA, long non-coding RNA.