Skip to main content
. 2018 May 14;19:78. doi: 10.1186/s12931-018-0778-z

Fig. 3.

Fig. 3

Effect of acute E-cigarette aerosol inhalation on alveolar macrophage genome-wide transcriptome profiles. a Volcano plot showing expression of all genes comparing baseline to post-EC exposure visit from AM of never-smokers who were exposed to acute inhalation of EC with nicotine (n = 7 subjects). Significance determined by p value < 0.05 (horizontal dashed line) and fold-change of post-EC exposure to baseline > 1.5 (vertical dashed lines). b Hierarchical clustering of differentially expressed genes from AM of never-smokers who were exposed to acute inhalation of EC with nicotine (n = 7 subjects). c Volcano plot showing expression of all genes comparing baseline to post-EC exposure visit from AM of never-smokers who were exposed to acute inhalation of EC without nicotine (n = 3 subjects). Significance determined by p value < 0.05 (horizontal dashed line) and fold-change of post-EC exposure to baseline > 1.5 (vertical dashed lines). d Hierarchical clustering of differentially expressed genes from AM of never-smokers who were exposed to acute inhalation of EC without nicotine (n = 3 subjects)