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. 2018 Mar 30;15(6):8582–8588. doi: 10.3892/ol.2018.8402

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Copyright: © Chen et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 2. — FOXP2 expression is downregulated in breast cancer compared with normal breast tissue. (A-D) Oncomine box plots of FOXP2 expression in TCGA and Bos breast cancer study (oncomine.org) comparing (A) invasive breast cancer (B) ILBC and (C) IDBC with normal breast tissue. (D) No significant differences were observed among patients with and without metastasis. (E) Protein expression level of FOXP2 in different cell lines. (F) Expression level of FOXP2 mRNA in different cell lines. Data were expressed as the mean ± standard deviation (n=3). (G) Relative mRNA expression of FOXP2 in 39 breast cancer patients and paired adjacent control tissue. (H) Alteration frequency of FOXP2 gene from cbioportal. ILBC, invasive lobular breast cancer; IDBC, invasive ductal breast cancer.