Figure 3.

Ability of a combination of VEGF, CEA, CA-125, and Cyfra 21-1 to distinguish between NSCLC and HC/BPN. Comparison of ROC curves of VEGF, CEA, CA-125, Cyfra 21-1, and a combination thereof between NSCLC cases and HC (A) and between NSCLC and BPN (B). ROC, receiver operating characteristic; VEGF, vascular endothelial growth factor; Cyfra 21-1, cytokeratin 19 fragments; CEA, carcinoembryonic antigen; CA-125, cancer antigen 125; NSCLC, non-small cell lung cancer; BPN, benign pulmonary nodules; HC, healthy controls