Table 4.
Multivariable logistic regression for the prediction of PLM
| Variable | Primary cohort (n = 782) | Validation cohort (n = 407) | |||||
|---|---|---|---|---|---|---|---|
| Odds ratio | 95% CI | P-value | Odds ratio | 95% CI | P-value | ||
| Age >50 (year) | 0.703 | 0.434-1.139 | 0.15 | 1.074 | 0.620-1.860 | 0.80 | |
| Preoperative SCC-Ag >3.26ng/mL | 4.106 | 2.589-6.511 | <0.05 | 3.022 | 1.720-5.309 | <0.05 | |
| Thrombocytosis | 1.311 | 0.757-2.269 | 0.33 | 1.135 | 0.623-2.067 | 0.68 | |
| FIGO stage (IIA vs. IA-IB) | 1.648 | 1.048-2.593 | <0.05 | 1.362 | 0.770-2.410 | 0.29 | |
| Grade (poor vs. others) | 0.817 | 0.488-1.366 | 0.44 | 1.022 | 0.532-1.964 | 0.95 | |
| PI (+) | 2.551 | 0.626-10.390 | 0.19 | 3.345 | 1.305-8.577 | <0.05 | |
| LVSI (+) | 5.031 | 2.531-10.002 | <0.05 | 7.132 | 3.928-12.949 | <0.05 | |
| DSI >2/3 | 1.525 | 0.968-2.404 | 0.07 | 0.763 | 0.427-1.364 | 0.36 | |
| Tumor size >4cm | 1.102 | 0.639-1.901 | 0.73 | 1.554 | 0.807-2.992 | 0.19 | |
SCC-Ag, squamous cell carcinoma antigen; FIGO, International Federation of Gynecology and Obstetrics; PI, parametrial involvement; LVSI, lymphovascular space involvement; DSI, depth of stromal invasion; PLM, pelvic lymphatic metastasis