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. 2018 Apr 18;9(9):1680–1688. doi: 10.7150/jca.24126

Table 3.

Coefficient of variations of allelic frequencies of each reference material determined by the NGS-based IVDs

Reference materials Coefficient of variations (%)
19del T790M L858R
Plasma-Q0 106 81 61
Plasma-Q1 89 66 48
Plasma-Q2 81 72 52
FFPE-Q1 58 26 27
FFPE-Q2 30 21 18

Abbreviations: EGFR, epidermal growth factor receptor; del, deletion; T, threonine; M, methionine; L, leucine; R, arginine; FFPE, formalin-fixed, paraffin-embedded.