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. 2018 Apr;13(4):645–646. doi: 10.4103/1673-5374.230288

Figure 1.

Figure 1

Cartoon representing the putative mechanism of action of ketamine and the molecular signalings involved in determining structural plasticity of dopaminergic neurons in vitro.

NMDAR: N-methyl-D-aspartate glutamate receptor; mTOR: mammalian target of rapamycin; ERK: extracellular regulated protein kinases; MEK: mitogen-activated protein kinase kinase; BDNF: brain derived neurotrophic factor; TrkB: tropomyosin receptor kinase B; GABA: gamma-aminobutyric acid.