TABLE 1.
Summary of FAERS search analysis
| Search terms | ||||||
|---|---|---|---|---|---|---|
|
|
||||||
| Drug | Reports | Events | Ketoacidosis | Acidosis (including metabolic and lactic) |
Cases with quantifiable data (present analysis) |
FDA confirmed cases9 (March 2013-May 2015) |
| SGLT2 inhibitors | ||||||
|
| ||||||
| Cana | 5371 | 11 028 | 137 | 50 | 39 | 48 |
|
| ||||||
| Dapa | 2061 | 4865 | 49 | 16 | 11 | 21 |
|
| ||||||
| Empa | 404 | 739 | 6 | 1 | 1 | 4 |
|
| ||||||
| Total | 7836 | 16 632 | 192 | 67 | 51 | 73 |
| All search terms: 259 | ||||||
|
| ||||||
| DPP4 inhibitors | ||||||
|
| ||||||
| Saxa | 4292 | 9012 | 7 | 21 | ND | NA |
|
| ||||||
| Sita | 26166 | 80 787 | 64 | 385 | ND | NA |
|
| ||||||
| Total | 30458 | 89 799 | 71 | 406 | NA | NA |
| All search terms: 477 | ||||||