Table 3.
Occurrence of Onset or Progression of Retinopathy From CSII Initiation According to Baseline Retinopathy, Duration of Diabetes, HbA1c at CSII Initiation, Average HbA1c Level Under CSII, and the Degree of Reduction in HbA1c at Year 1.
| Number of events (% of patients) | P value | |
|---|---|---|
| Baseline retinopathy | ||
| NDR | 9 (11.5%) | |
| NPDR | 3 (11.5%) | NS (vs NDR) |
| PDR | 7 (29.2%) | .04 (vs NDR) |
| Duration of diabetes | ||
| <15 years | 3 (4.3%) | |
| >15 years | 16 (27.1%) | <.01 |
| Baseline HbA1c | ||
| <8% (64 mmol/mol) | 5 (10.4%) | |
| ⩾8% (64 mmol/mol) | 14 (17.5%) | NS |
| Average HbA1c under CSII | ||
| <8% (64 mmol/mol) | 12 (15.2%) | |
| ⩾8% (64 mmol/mol) | 7 (14.3%) | NS |
| Reduction of HbA1c after one year | ||
| <0 | 5 (19.2%) | |
| 0-1% (0-11 mmol/mol) | 8 (13.6%) | NS |
| >1% (>11 mmol/mol) | 6 (15.8%) | NS |
Progression of retinopathy defined on laser photocoagulation in patients with NPDR or supplement laser photocoagulation or vitrectomy in patients with PDR at CSII initiation.