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. Author manuscript; available in PMC: 2018 May 14.
Published in final edited form as: Am J Obstet Gynecol. 2017 Oct 13;217(6):682.e1–682.e13. doi: 10.1016/j.ajog.2017.10.001

TABLE 2.

the 2.5th, 10th, 50th, 90th, and 97.5th centiles of the concentrations of PlGF, sVEGFR-1, and sEng, and the ratios of PlGF/sVEGFR-1 and PlGF/sEng, according to gestational age at sample collection.

PlGF (pg/mL) sVEGFR1 (pg/mL) sEng (ng/mL) PlGF/sVEGFR1 (PlGF/sEng) x 1000
GA(weeks) 2.5th 10th 50th 90th 97.5th GA(weeks) 2.5th 10th 50th 90th 97.5th GA(weeks) 2.5th 10th 50th 90th 97.5th GA(weeks) 2.5th 10th 50th 90th 97.5th GA(weeks) 2.5th 10th 50th 90th 97.5th
12 17.3 25.3 45.4 88.4 132.4 12 384.8 513.9 970.8 1650.2 2364.6 12 4.28 5.09 6.84 9.01 11.37 12 0.012 0.023 0.047 0.118 0.169 12 2.2 3.6 6.6 13.9 20.9
13 21.5 32.3 58.0 117.8 180.2 13 376.2 516.6 962.1 1695.5 2501.5 13 4.21 5.01 6.68 8.88 11.32 13 0.016 0.029 0.060 0.156 0.228 13 2.8 4.6 8.6 18.4 28.7
14 26.6 40.8 73.3 154.1 238.9 14 363.8 511.9 951.9 1733.5 2613.8 14 4.12 4.91 6.50 8.70 11.14 14 0.020 0.036 0.077 0.202 0.306 14 3.6 5.9 11.2 24.2 38.7
15 32.8 50.9 91.6 198.0 309.5 15 349.6 502.0 940.1 1761.7 2696.7 15 4.03 4.82 6.32 8.50 10.88 15 0.026 0.046 0.098 0.259 0.404 15 4.6 7.5 14.4 31.4 51.1
16 40.3 62.8 113.5 250.3 392.9 16 335.2 488.9 926.8 1778.5 2748.6 16 3.95 4.72 6.15 8.29 10.56 16 0.033 0.057 0.123 0.327 0.525 16 5.9 9.4 18.4 40.3 66.1
17 49.3 76.7 139.4 311.6 490.0 17 321.7 474.4 912.6 1783.9 2770.6 17 3.87 4.62 5.99 8.07 10.22 17 0.042 0.071 0.154 0.408 0.673 17 7.5 11.8 23.3 51.2 84.0
18 59.8 92.8 169.8 382.4 601.8 18 309.9 460.1 898.2 1779.2 2766.8 18 3.79 4.54 5.85 7.86 9.88 18 0.053 0.088 0.192 0.502 0.846 18 9.4 14.6 29.2 64.3 104.8
19 71.9 110.8 205.0 463.1 728.6 19 300.5 446.9 884.3 1766.5 2743.0 19 3.73 4.46 5.73 7.66 9.58 19 0.064 0.109 0.236 0.611 1.045 19 11.6 18.0 36.1 79.5 128.5
20 85.4 130.8 245.2 553.7 871.0 20 293.6 436.0 872.1 1748.8 2706.7 20 3.68 4.40 5.63 7.50 9.34 20 0.077 0.132 0.287 0.734 1.266 20 14.0 21.7 44.1 97.0 155.0
21 100.0 152.4 290.2 654.0 1028.5 21 289.5 427.8 862.3 1729.5 2665.5 21 3.64 4.36 5.56 7.38 9.17 21 0.091 0.158 0.344 0.870 1.503 21 16.7 25.8 52.9 116.6 184.0
22 115.2 174.9 339.8 763.3 1200.5 22 288.3 423.0 856.2 1712.4 2627.5 22 3.62 4.33 5.53 7.30 9.09 22 0.104 0.185 0.406 1.016 1.748 22 19.4 30.0 62.5 137.9 214.9
23 130.4 197.6 392.9 880.5 1385.0 23 290.2 422.0 854.7 1701.2 2600.3 23 3.61 4.32 5.52 7.29 9.12 23 0.115 0.211 0.471 1.169 1.991 23 21.9 34.1 72.3 160.4 247.0
24 144.7 219.6 448.2 1004.0 1579.4 24 295.2 425.2 859.0 1699.7 2591.1 24 3.61 4.33 5.55 7.33 9.26 24 0.124 0.234 0.535 1.324 2.220 24 23.9 37.8 82.0 183.5 279.5
25 157.2 239.6 503.7 1131.4 1779.6 25 303.5 433.1 870.2 1711.7 2607.2 25 3.64 4.35 5.62 7.46 9.55 25 0.129 0.252 0.594 1.472 2.426 25 25.2 40.7 91.0 206.1 311.4
26 167.0 256.4 556.8 1259.6 1980.3 26 315.1 446.0 889.7 1741.3 2655.8 26 3.68 4.40 5.73 7.66 9.99 26 0.129 0.261 0.642 1.605 2.596 26 25.6 42.5 98.7 227.3 341.4
27 173.4 268.9 604.7 1384.7 2174.8 27 330.2 464.6 918.8 1792.7 2744.9 27 3.73 4.47 5.87 7.96 10.62 27 0.125 0.261 0.676 1.716 2.723 27 25.1 43.0 104.5 245.9 368.5
28 175.9 276.3 644.4 1502.1 2355.7 28 349.0 489.3 959.4 1871.0 2883.9 28 3.81 4.56 6.05 8.37 11.46 28 0.117 0.251 0.690 1.796 2.799 28 23.6 42.0 107.8 260.8 391.4
29 174.3 278.0 672.9 1606.6 2514.5 29 371.6 520.9 1013.3 1981.9 3083.9 29 3.90 4.67 6.28 8.91 12.56 29 0.105 0.232 0.683 1.837 2.822 29 21.3 39.8 108.4 271.1 409.1
30 168.7 273.9 688.0 1692.5 2643.0 30 398.0 560.3 1082.9 2132.4 3358.8 30 4.00 4.80 6.55 9.58 13.93 30 0.091 0.206 0.655 1.834 2.792 30 18.6 36.4 106.1 276.0 420.7
31 159.7 264.3 688.1 1753.8 2733.6 31 428.4 608.2 1171.0 2330.8 3725.7 31 4.12 4.95 6.86 10.40 15.63 31 0.077 0.175 0.607 1.787 2.711 31 15.7 32.3 101.2 275.2 425.5
32 148.2 250.2 672.9 1785.2 2780.1 32 462.8 665.5 1280.5 2587.1 4205.1 32 4.25 5.11 7.22 11.40 17.69 32 0.062 0.144 0.545 1.698 2.585 32 12.9 27.9 94.0 268.7 423.3
33 135.0 232.5 643.3 1782.1 2778.6 33 501.0 733.1 1415.0 2912.5 4820.9 33 4.40 5.29 7.62 12.57 20.11 33 0.049 0.115 0.473 1.571 2.423 33 10.3 23.5 85.2 256.8 414.0
34 121.1 212.6 601.2 1741.4 2728.1 34 542.7 811.6 1577.7 3318.7 5597.7 34 4.55 5.48 8.06 13.91 22.87 34 0.038 0.089 0.398 1.416 2.233 34 8.2 19.4 75.3 240.2 398.1
35 107.4 191.9 549.7 1662.3 2630.7 35 587.7 901.2 1771.9 3816.6 6557.3 35 4.70 5.67 8.53 15.42 25.87 35 0.029 0.068 0.325 1.244 2.023 35 6.5 15.8 65.1 219.9 376.3
36 94.5 171.5 492.2 1546.7 2491.3 36 635.3 1001.8 1999.4 4412.4 7709.5 36 4.86 5.86 9.02 17.03 28.95 36 0.022 0.051 0.259 1.065 1.804 36 5.2 12.9 55.1 197.2 349.6
37 83.1 152.4 432.1 1399.3 2317.9 37 684.7 1112.1 2260.1 5102.6 9038.7 37 5.00 6.04 9.53 18.68 31.80 37 0.017 0.039 0.202 0.889 1.584 37 4.3 10.5 45.8 173.1 319.2
38 73.3 135.4 372.8 1227.6 2119.9 38 735.3 1229.7 2549.7 5866.0 10483.9 38 5.13 6.20 10.03 20.23 34.01 38 0.013 0.030 0.155 0.725 1.368 38 3.8 8.7 37.6 148.9 286.4
39 65.5 120.9 317.0 1041.4 1907.6 39 786.1 1350.7 2858.3 6654.4 11917.8 39 5.23 6.32 10.50 21.49 35.09 39 0.010 0.023 0.117 0.578 1.164 39 3.5 7.4 30.4 125.6 252.6
40 59.6 109.4 266.4 851.6 1691.3 40 836.3 1469.3 3167.7 7383.6 13132.3 40 5.29 6.40 10.91 22.26 34.55 40 0.008 0.019 0.089 0.452 0.975 40 3.7 6.6 24.5 103.9 219.0

Concentrations are given in pg/mL for PlGF and sVEGFR-1 and ng/mL for sENG. Values for the PlGF/sENG ratio were multiplied by 1,000. Of note, by dividing the percentile values to the corresponding median value (50th percentile), one can obtain multiple of median (MOM) cut-offs.