Table 4.

Inductors of major CYP isozymes

CYP isozyme	Potent inducers	Moderate inducers	Weak inducers
1A2		Montelukast, tobacco smoke, phenytoin	Moricizine, omeprazole, phenobarbital
2C9		Arbamazepine, rifampicin	Aprepitant, bosentan, phenobarbital, St John’s wort extract
2C19		Rifampicin, S-mephenytoin	Artemisinin
2D6	Inducers are not identified		Inducers are not identified
3A4	Avasimibe, carbamazepine, rifampicin, phenytoin, St John’s wort extract	Bosentan, modafinil, nafcillin, etravirine, efavirenz, lurasidone	Aprepitant, armodafinil, pioglitazone, prednisolone, refinamid, echinacea extract

Note: Data from Wu et al.52

Abbreviation: CYP, cytochrome.