Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 May 8;11:2657–2672. doi: 10.2147/OTT.S162281

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2018 Shi et al. This work is published and licensed by Dove Medical Press Limited

The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

PMC Copyright notice

CIK inhibition effects for BGC823 tumor growth in nude mouse xenograft models. Mice in experimental groups were treated by injection of either unpurified CIK cells or purified CIK cells, along with a control group in which mice were injected with PBS. The tumor inhibition rates (A), tumor weight (B), and tumor size (C) in nude mouse xenograft models were measured in both the groups. Statistical analysis shows that the co-culture group (RBC:PBMC =20:1, 50:1) and unpurified CIK showed a better therapeutic potential against cancer than purified CIK in vivo (n=10 in each group, P<0.05). Compared with the control group, *P<0.05; Compared with the purified group, ^ΔP<0.05.

Abbreviations: CIK cells, cytokine-induced killer cells; U-CIK, CIK in unpurified group; R:M, RBC:PBMC; RBC, red blood cell; PBMC, peripheral blood mononuclear cell.