Table 1. Expression levels of highly expressed transcripts in hematopoietic supportive cell lines.
| Gene ID (Zv9) | Gene name | Gene description | RPKM (ZKS cells) | RPKM (ZEST cells) | RPKM (CHEST cells) |
|---|---|---|---|---|---|
| ENSDARG00000056680 | stc2a | Stanniocalcin 2a | 1171.390702 | 1231.42446 | 706.1714178 |
| ENSDARG00000015050 | calm3a | Calmodulin 3a (phosphorylase kinase, delta) | 398.2576181 | 445.6855878 | 969.0665779 |
| ENSDARG00000026726 | anxa1a | Annexin A1a | 386.1286169 | 280.2930981 | 417.0527221 |
| ENSDARG00000071498 | fhl1a | Four and a half LIM domains 1a | 392.740221 | 209.8129055 | 350.3135956 |
| ENSDARG00000055439 | adamtsl7 | ADAMTS-like 7 | 377.7311012 | 296.1991765 | 268.6541787 |
| ENSDARG00000069752 | ckba | Creatine kinase, brain a | 410.942751 | 156.7429014 | 276.7297589 |
| ENSDARG00000016691 | cd9b | CD9 antigen, b | 506.2882968 | 266.2312285 | 66.00918816 |
| ENSDARG00000093440 | tnfaip6 | Tumor necrosis factor, alpha-induced protein 6 | 197.4394341 | 109.3081398 | 491.6323329 |
| ENSDARG00000038123 | myl9a | Myosin, light chain 9a, regulatory | 179.6584981 | 96.56364658 | 511.0645904 |
| ENSDARG00000014626 | dlx3b | Distal-less homeobox gene 3b | 285.6044597 | 300.5094173 | 166.0309536 |
| ENSDARG00000087402 | tpm1 | Tropomyosin 1 (alpha) | 147.8702844 | 67.17783708 | 530.8673917 |
| ENSDARG00000029353 | serpine2 | Serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 155.1438879 | 185.8865435 | 362.6601572 |
| ENSDARG00000008359 | cnn3a | Calponin 3, acidic a | 200.6466151 | 175.5868376 | 322.1817671 |
| ENSDARG00000013804 | capns1b | Calpain, small subunit 1 b | 295.8800252 | 192.2972637 | 137.1191417 |
| ENSDARG00000062363 | phex | Phosphate regulating gene with homologues to endopeptidases on the X chromosome | 374.7902084 | 246.0473474 | 2.923096804 |
| ENSDARG00000007697 | fabp7a | Fatty acid binding protein 7, brain, a | 195.9918097 | 237.0929702 | 156.4171196 |
| ENSDARG00000054749 | lmo4b | LIM domain only 4b | 171.4754089 | 158.0390988 | 259.5479538 |
| ENSDARG00000040362 | ehd2 | EH-domain containing 2 | 161.7766861 | 245.0843826 | 179.9114927 |
| ENSDARG00000012066 | dcn | Decorin | 138.738941 | 110.0299673 | 294.5159175 |
| ENSDARG00000007396 | rnd3b | Rho family GTPase 3b | 230.919067 | 106.1477521 | 180.3513591 |
| ENSDARG00000075045 | cxcl-c1c | Chemokine (C-X-C motif) ligand C1c | 205.5342189 | 222.3706168 | 85.84923297 |
| ENSDARG00000030449 | crabp2b | Cellular retinoic acid binding protein 2, b | 105.0984741 | 221.8625863 | 181.7852462 |
| ENSDARG00000089187 | wfdc2 | WAP four-disulfide core domain 2 | 215.3192844 | 100.2819887 | 173.5050759 |
| ENSDARG00000061226 | timp2a | Tissue inhibitor of metalloproteinase 2a | 110.5132145 | 134.7435353 | 217.234448 |
| ENSDARG00000030694 | atp6v1e1b | ATPase, H+ transporting, lysosomal, V1 subunit E isoform 1b | 211.5850639 | 104.0432062 | 140.8175355 |
| ENSDARG00000016238 | arl6ip5b | ADP-ribosylation factor-like 6 interacting protein 5b | 180.1080903 | 105.0459892 | 159.1043514 |
| ENSDARG00000019307 | dusp5 | Dual specificity phosphatase 5 | 126.478358 | 236.8883821 | 68.27162288 |
| ENSDARG00000054823 | id3 | Inhibitor of DNA binding 3 | 123.0298414 | 119.957024 | 185.8068645 |
| ENSDARG00000096118 | ost4 | Oligosaccharyltransferase 4 homolog | 293.697141 | 56.14183101 | 47.90212635 |
| ENSDARG00000070391 | tspan4b | Tetraspanin 4b | 124.4627775 | 134.439824 | 107.2748044 |
| ENSDARG00000002507 | itga10 | Integrin, alpha 10 | 89.61611629 | 201.1502394 | 71.71587866 |
| ENSDARG00000008363 | mcl1b | Myeloid cell leukemia sequence 1b | 138.0029954 | 100.3628761 | 121.8545135 |
| ENSDARG00000078674 | hspb9 | Heat shock protein, alpha-crystallin-related, 9 | 208.1065389 | 130.9142075 | 9.6011956 |
| ENSDARG00000056627 | cxcl14 | Chemokine (C-X-C motif) ligand 14 | 30.54406211 | 119.5273691 | 197.7629774 |
| ENSDARG00000026070 | cd82b | CD82 antigen, b | 117.1867309 | 119.7501676 | 99.79403009 |
| ENSDARG00000032831 | htra1a | HtrA serine peptidase 1a | 62.04851894 | 79.54294838 | 191.2823828 |
| ENSDARG00000027088 | ptgdsb | Prostaglandin D2 synthase b | 295.7620764 | 16.83617366 | 7.299828587 |
| ENSDARG00000069983 | scinla | Scinderin like a | 229.2763242 | 77.71766924 | 12.73139596 |
| ENSDARG00000014103 | dkk1a | Dickkopf 1a | 45.36030464 | 95.82598311 | 174.3537947 |
| ENSDARG00000044001 | lgals3l | Lectin, galactoside-binding, soluble, 3 (galectin 3)-like | 151.485882 | 94.79980323 | 68.69664737 |
| ENSDARG00000094752 | rpe65b | Retinal pigment epithelium-specific protein 65b | 51.81279893 | 157.9199935 | 85.8643745 |
| ENSDARG00000006275 | irf2bp2b | Interferon regulatory factor 2 binding protein 2b | 83.23427126 | 90.32706729 | 118.4504944 |
| ENSDARG00000096594 | lratb | Lecithin retinol acyltransferase b (phosphatidylcholine—retinol O-acyltransferase b) | 54.62075299 | 126.7544822 | 101.4833434 |
| ENSDARG00000045219 | dkk1b | Dickkopf 1b | 115.2674028 | 123.3601222 | 41.36781122 |
| ENSDARG00000073891 | gdf10b | Growth differentiation factor 10b | 33.67260166 | 219.1972506 | 6.710000293 |
| ENSDARG00000063704 | gpr1 | G protein-coupled receptor 1 | 11.47967914 | 67.08867022 | 174.2527408 |
| ENSDARG00000042690 | s1pr1 | Sphingosine-1-phosphate receptor 1 | 51.05707689 | 120.3548169 | 69.24951973 |
| ENSDARG00000070420 | cyp24a1 | Cytochrome P450, family 24, subfamily A, polypeptide 1 | 18.72705544 | 177.0835255 | 44.13670934 |
| ENSDARG00000086842 | dap1b | Death associated protein 1b | 108.3112632 | 77.42847935 | 53.19516114 |
| ENSDARG00000068710 | nid1a | Nidogen 1a | 62.19315736 | 114.8440231 | 50.83336553 |
| ENSDARG00000055381 | bambia | BMP and activin membrane-bound inhibitor homolog a | 88.97243166 | 57.43071367 | 78.67391423 |
| ENSDARG00000067742 | eva1bb | Eva-1 homolog Bb | 63.44368564 | 84.2765728 | 74.97828951 |
| ENSDARG00000005789 | enpp1 | Ectonucleotide pyrophosphatase/ phosphodiesterase 1 | 64.34284892 | 137.6726653 | 19.82855613 |
| ENSDARG00000056023 | hoxb9a | Homeo box B9a | 69.19604476 | 83.45231228 | 68.31730246 |
| ENSDARG00000094857 | dio2 | Deiodinase, iodothyronine, type II | 79.95831483 | 112.2283984 | 26.87641183 |
| ENSDARG00000089078 | col23A1 | Collagen, type XXIII, alpha 1 | 63.62339938 | 147.7007832 | 2.289688031 |
| ENSDARG00000030177 | uchl3 | Ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) | 105.7558676 | 48.45357406 | 49.98198164 |
| ENSDARG00000024877 | ptgr1 | Prostaglandin reductase 1 | 103.6331577 | 54.73419065 | 37.55761808 |
| ENSDARG00000094854 | ms4a17a.8 | Membrane-spanning 4-domains, subfamily A, member 17A.8 | 116.1375676 | 55.21694763 | 23.36757024 |
| ENSDARG00000019128 | tpm4b | Tropomyosin 4b | 54.49279439 | 41.58138656 | 98.05974096 |
| ENSDARG00000058348 | scinlb | Scinderin like b | 43.90721933 | 56.88955333 | 90.22067671 |
| ENSDARG00000005541 | wif1 | Wnt inhibitory factor 1 | 93.47095208 | 67.6434638 | 28.05685047 |
| ENSDARG00000010462 | sp9 | Sp9 transcription factor | 57.92009712 | 49.7884664 | 76.65945541 |
| ENSDARG00000044803 | dhrs3b | Dehydrogenase/reductase (SDR family) member 3b | 130.0154057 | 51.68314191 | 1.624036879 |
| ENSDARG00000087263 | ssr3 | Signal sequence receptor, gamma | 91.92315352 | 47.64499378 | 39.03838439 |
| ENSDARG00000058733 | ihha | Indian hedgehog homolog a | 7.794542694 | 88.86938529 | 78.16679263 |
| ENSDARG00000015966 | yaf2 | YY1 associated factor 2 | 67.3993785 | 69.0931997 | 38.15094538 |
| ENSDARG00000090945 | clec4f | C-type lectin domain family 4, member F | 120.1210729 | 48.41536445 | 3.207217092 |
| ENSDARG00000042296 | dlx5a | Distal-less homeobox gene 5a | 126.8385026 | 31.88420836 | 12.30766798 |
| ENSDARG00000053381 | ppap2a | Phosphatidic acid phosphatase type 2A | 36.20007779 | 67.05858162 | 65.57173276 |
| ENSDARG00000069376 | tnfsf12 | Tumor necrosis factor (ligand) superfamily, member 12 | 38.06281765 | 121.2490869 | 7.954191675 |
All transcripts are presented as reads per kilobase of transcript per million reads mapped (RPKM). Each stromal cell line’s transcriptome was analyzed and compared to a non-hematopoietic supportive stromal cell line (ZF4). The transcripts below have been described previously as playing a role in hematopoiesis.