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. 2018 May 14;13(5):e0197407. doi: 10.1371/journal.pone.0197407

Fig 1. Influenza HA, exendin-4 and vatreptacog alfa peptides binding to HLA class II alleles.

Fig 1

Experimental measured binding affinities of (A) Influenza HA, (B) exendin-4 and (C) vatreptacog alfa peptides to 26 alleles. The dotted line indicates IC50 of 1000 nM. The solid black dots indicate alleles that the peptide bind and the open dots indicate non-binding alleles. Comparison of measured and predicted binding data on (D) 13-mer and 15-mer influenza HA epitopes, and (E) exendin-4 and (F) vatreptacog alfa. Affinities are expressed in terms of IC50 nM. The association between the datasets was calculated using a non-parametric two-tailed Spearman rank correlation.