Table 1. Demographic and clinical characteristics of the population evaluated.
| Lean normotensive subjects (n = 24) | Lean hypertensive patients (n = 12) | Obese patients (n = 32) |
|
|---|---|---|---|
| Gender (males: M) | 14M (58%) | 7 M (58%) | 7 M (28%) |
| Age (years) | 48.1±15.0 | 60.9±8.83 * | 42.0±14.5 ## |
| Body mass index (Kg/m2) | 25.1±2.92 | 26.2±3.84 | 42.9±5.07 ***### |
| Systolic blood pressure (mm Hg) | 122±10.9 | 134±17.0 * | 129±18.1 |
| Diastolic blood pressure (mm Hg) | 76.3±9.35 | 76.6±9.96 | 82.0±12.6 |
| C reactive protein (mg/L) | 7.13±7.31 | 1.55±1.12 | 8.41±4.71 # |
| Serum glucose (mg/dl | 90.7±11.9 | 98.4±15.3 | 103±37.5 |
| Serum creatinine (mg/dl) | 0.81±0.23 | 0.95 ±0.23 | 0.72±0.11 |
| Creatinine clearance (ml/min) | 94.9±23.6 | 76.9 ±16.5 | 116±34.8 |
| Blood urinary nitrogen (mg/ml) | 37.6±14.0 | 41.6±13.6 | 30.1±8.53 |
| Serum uric acid (mg/dl) | 4.52±1.42 | 5.54±1.84 | 4.68±1.28 |
| Serum sodium (mEq/L) | 141±2.00 | 142±1.53 | 140±2.06 |
| Serum potassium (mEq/L) | 3.87±0.47 | 3.93±0.47 | 3.80±0.28 |
| Serum chloride (mEq/L) | 105±2.43 | 105±2.31 | 105±1.74 |
| Serum triglycerides (mg/dl) | 76.7±33.9 | 93.2±30.8 | 119±57.7 |
| Serum cholesterol (mg/dl) | 179±25.2 | 180±34.2 | 185±28.8 |
* P<0.05,
*** P<0.001 vs. Lean normotensive subjects;
# P<0.05,
## P<0.001,
### P<0.001 vs. Lean hypertensive patients. Creatinine clearance: MDRD formula. Data are expressed as mean±standard deviation.