Table 6. Pneumococcal antibody opsonic indicies and antibody potency in serum of three burn and eight neurosurgical serum samples.

Capsular Serotype	Patient Population a	Median OI	Range OI	Median Antibody Potency (OI/IgG)	Range Antibody Potency (OI/IgG)
1	Burn Post-PPSV23	1292	496–1748	200	154–598
	Neurosurgical Post-PPSV23	230	13–1657	47	8–200
	Neurosurgical Pre-PPSV23	8	4–11	32	5–74
3	Burn Post-PPSV23	391	241–464	127	48–552
	Neurosurgical Post-PPSV23	1033	431–1264	190	50–392
	Neurosurgical Pre-PPSV23	73	28–116	127	35–240
5	Burn Post-PPSV23	1046	313–7109	191	15–290
	Neurosurgical Post-PPSV23	201	13–381	21	16–31
	Neurosurgical Pre-PPSV23	16	4–50	40	1–69
6B	Burn Post-PPSV23	3427	901–6764	285	91–9395
	Neurosurgical Post-PPSV23	2419	1245–26302	786	298–114357
	Neurosurgical Pre-PPSV23	77	12–329	186	39–658
7F	Burn Post-PPSV23	12358	11855–12779	1236	686–5444
	Neurosurgical Post-PPSV23	15848	923–76009	1632	63–8244
	Neurosurgical Pre-PPSV23	766	361–7245	1540	156–7875
14	Burn Post-PPSV23	11551	10491–24596	510	277–6244
	Neurosurgical Post-PPSV23	3427	1402–37826	245	78–17594
	Neurosurgical Pre-PPSV23	722	481–1254	1013	687–1326
23F	Burn Post-PPSV23	1191	536–32242	412	67–1757
	Neurosurgical Post-PPSV23	798	4–2968	187	10–223
	Neurosurgical Pre-PPSV23	73	4–376	163	21–291

PPSV23, 23-valent pneumococcal polysaccharide vaccine; OI, Opsonic index (reciprocal of the interpolated serum dilution that kills 50% of the bacteria). For reporting purposes, serum that killed less than 50% of the bacteria are reported as 4, which is one half the lowest dilution of the serum tested. IgG, Immunoglobulin concentration as microgram per milliliter.

a, Three burn and four neurosurgical post PPSV23 samples and four neurosurgical pre PPSV23 samples were able to be analyzed due to the presence of anti-pneumococcal antibiotics being detected in the remaining samples