Skip to main content
. Author manuscript; available in PMC: 2018 Aug 28.
Published in final edited form as: Nature. 2018 Feb 28;556(7699):57–63. doi: 10.1038/nature26155

Extended Data Figure 4. Transcriptional activation with xCas9 2.0.

Extended Data Figure 4

a–d, The transcriptional activator dxCas9(2.0)–VPR was tested on the R1 protospacer (Extended Data Fig. 3 and Supplementary Table 8) with each of the 64 possible NNN PAMs (NAN, NCN, NGN, and NTN) in HEK293T cells. Values and error bars reflect the mean and s.d. of n=3 biologically independent samples.