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. Author manuscript; available in PMC: 2018 Dec 14.
Published in final edited form as: J Phys Chem B. 2017 Nov 30;121(49):11072–11084. doi: 10.1021/acs.jpcb.7b08785

Table 2.

Translational diffusion coefficients of villin at different concentrations

[villin]
(mM)		 Np Dt ;< 1 ns
(nm2/ns; slow-down)		 Dt ; 1–10 ns
(nm2/ns; slow-down)		 Dt ;10–100 ns
(nm2/ns, slow-down)
dilute 1 0.49 (0.004) 1 0.48 (0.008) 1 0.46 (0.03) 1
8 8 0.43 (0.01) 0.88 0.41 (0.01) 0.85 0.40 (0.02) 0.87
16 8 0.35 (0.007) 0.71 0.34 (0.006) 0.71 0.31 (0.01) 0.67
32 8 0.25 (0.008) 0.51 0.24 (0.009) 0.50 0.22 (0.01) 0.48
32 64 0.21 (0.004) 0.43 0.18 (0.004) 0.38 0.16 (0.004) 0.35

Error estimates from averaging over blocks (dilute solution) and protein copies (concentrated solution) are given in parentheses. For each value, the slow-down relative to diffusion in dilute solvent is given in bold.