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. Author manuscript; available in PMC: 2019 Apr 18.
Published in final edited form as: J Am Chem Soc. 2018 Apr 3;140(15):5153–5160. doi: 10.1021/jacs.8b00593

Figure 3.

Figure 3

Effect of pH on the intra-helical and extra-helical lifetimes. A) Sample i-t traces for different single molecules of dsDNA in the α-HL nanopore as a function of pH (6.0 – 7.5). Data were recorded at -70 mV and 20 °C. The solution contains 250 mM KCl and 10 mM phosphate buffer. B) Intra-helical (red) and extra-helical (blue) lifetimes of a C:C mismatch as a function of pH.