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. Author manuscript; available in PMC: 2018 May 14.
Published in final edited form as: Biol Psychiatry. 2017 Sep 20;83(3):244–253. doi: 10.1016/j.biopsych.2017.09.006

Table 2.

Female-Only Meta-analysis of the Effect of Posttraumatic Stress Disorder on Subcortical Region Volumes Adjusting for Age and Intracranial Volume

Region Cohen’s d (95% CI) SE p Value %diff I2 phet Cases Control Subjects
Nucleus Accumbens −0.22 (−0.39 to −0.061) 0.083 .0071a −2.32 1.50 .16 305 427
Amygdala −0.14 (−0.30 to 0.015) 0.081 .075 −1.46 0.0047 .18 307 427
Caudate 0.008 (−0.15 to 0.17) 0.081 .92 0.19 0.00 .67 307 429
Hippocampus −0.31 (−0.47 to −0.15) 0.081 .00012b −2.42 0.00 .90 308 428
Lateral Ventricle 0.081 (−0.077 to 0.24) 0.081 .32 3.49 0.00 .87 308 430
Pallidum 0.10 (−0.12 to 0.32) 0.11 .39 1.13 35.30 .068 293 414
Putamen −0.051 (−0.21 to 0.11) 0.083 .54 −0.49 0.0064 .60 291 416
Thalamus −0.13 (−0.32 to 0.073) 0.10 .22 −0.84 23.74 .12 299 419

CI, confidence interval.

a

Comparison was significant at the p < .05 level.

b

Comparison was significant after a Bonferroni correction for eight subcortical regions examined (p < .0063).