Table 1.

Considerations for UE neurological and functional activity outcome measurement tools in biological and pharmacological clinical trials according to trial phase and ICF domains

^aThese COAs measure components of body structure and function and activity

^bThese recently developed COAs may provide additional insight and have been attracting attention in the field of SCI but are not fully explored and require further application/validation in clinical trials

^cSCAR combines selected ordinal aspects of ISNCSCI and SCIM III and transforms those scores into a linear continuous scales, thus a separate assessment is not required