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. 2018 May 14;8:7503. doi: 10.1038/s41598-018-25918-3

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Antibody patterns in individual sera with 130 selected Ct antigens. (a) Each microarray comprised 8 blocks and each block contained the same 130 Ct antigens and 10 negative controls (NC1). Individual blocks were incubated with serum from a Ct-uninfected woman (topmost block), and seven Ct-infected cervical cancer patients. (b) Enlarged view of antibody reactivity patterns in single sera from Ct-infected women, the top two being cancer-free and the bottom two with cervical cancer. Boxed spots highlight potential markers for general Ct infection (green) and cervical cancer (blue).