Table 3.
Treatment toxicity
| Grade | 1 | 2 | 3 | 4 |
|---|---|---|---|---|
| N = 65 | n (%) | n (%) | n (%) | n (%) |
| Neutropenia | 19 (29.2) | 20 (30.7) | 12 (18.4) | 4 (6.1) |
| Thrombocytopenia | 19 (29.2) | 10 (15.3) | 3 (4.6) | 0 |
| Anaemia | 27 (41.5) | 15 (23.0) | 1 (1.5) | 0 |
| Vomiting | 7 (10.7) | 4 (6.1) | 1 (1.5) | 0 |
| Fever | 1 (1.5) | 2 (3.0) | 0 | 0 |
| Fatigue | 9 (13.8) | 6 (9.2) | 1 (1.5) | 0 |
| Alopecia | 10 (15.3) | 6 (9.2) | 0 | 0 |
| Hypoalbuminaemia | 13 (20.0) | 3 (4.6) | 0 | 0 |
| ALTa | 3 (4.6) | 0 | 0 | 0 |
| Radiation dermatitis | 8 (12.3) | 8 (12.3) | 1 (1.5) | 0 |
| Oesophagitis | 19 (29.2) | 19 (29.2) | 3 (4.6) | 0 |
| Hypocalcaemia | 8 (12.3) | 1 (1.5) | 0 | 0 |
| Hypomagnesaemia | 2 (3.0) | 1 (1.5) | 0 | 0 |
| Hyponatraemia | 8 (12.3) | 0 | 0 | 0 |
| Hypophosphataemia | 4 (6.1) | 0 | 1 (1.5) | 0 |
| Constipation | 2 (3.0) | 6 (9.2) | 0 | 0 |
| Diarrhoea | 1 (1.5) | 2 (3.0) | 0 | 0 |
| Peripheral sensory neuropathy | 2 (3.0) | 12 (18.4) | 0 | 0 |
| Pneumonitis | 5 (7.6) | 7 (10.7) | 1 (1.5) | 0 |
| Hypopotassaemia | 3 (4.6) | 0 | 0 | 0 |
| Hoarseness | 7 (10.7) | 2 (3.0) | 0 | 0 |
| Ventricular arrhythmia | 3 (4.6) | 0 | 0 | 0 |
| Pericardial effusion | 4 (6.1) | 0 | 0 | 0 |
Toxicity was graded according to the National Cancer Institute Common Toxicity Criteria, version 4.0
aAlanine aminotransferase increased