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. 2018 May 8;9:956. doi: 10.3389/fimmu.2018.00956

Figure 6.

Figure 6

Hypothetical model of extracellular vesicle (EV) interaction with monocytes. In this model, acute infection results in augmented release of EVs from cells, particularly granulocytes, which are ingested by monocytes. Activated monocytes can then differentiate and migrate to tissues, which can increase tissue inflammation and damage. Abbreviations: PMN, polymorphonuclear cell (granulocyte); Plt, platelet.