Table 2. Specific discrepancy between Phadiatop and previous ImmunoCAP findings in small subsets of asthmatics and non-asthmatic controls.
Subset | Subject ID# | hx2 (kUA/L) | mx2 (kUA/L) | tx4 (kUA/L) | wx5 (kUA/L) | Phadiatop (kUA/L) |
---|---|---|---|---|---|---|
Subset A | E3001006 | 4.66 | 0.31 | 0.86 | 0.70 | 30.93 |
E1005006 | 0.98 | 0.06 | 0.08 | 0.04 | 13.21 | |
E1007002 | 0.70 | 0.13 | 0.06 | 0.04 | 6.82 | |
E1005017 | 0.02 | 0.03 | 0.87 | 0.25 | 5.34 | |
E3006019 | 0.61 | 0.06 | 0.08 | 0.26 | 6.24 | |
Subset B | E1009009 | 0.12 | 0.36 | 0.13 | 0.07 | 0.33 |
E1006004 | 0.11 | 0.41 | 0.10 | 0.07 | 0.30 | |
E3001018 | 0.07 | 0.43 | 0.07 | 0.04 | 0.29 | |
E2001005 | 0.05 | 0.48 | 0.04 | 0.04 | 0.22 | |
E2008005 | 0.03 | 0.37 | 0.06 | 0.02 | 0.12 | |
E2004002 | 0.02 | 0.76 | 0.08 | 0.03 | 0.09 | |
E3006020 | 0.01 | 0.90 | 0.04 | 0.03 | 0.07 | |
E1004039 | 0.03 | 0.38 | 0.08 | 0.03 | 0.07 | |
Subset C | E1004001 | 0.02 | 0.11 | 0.04 | 0.04 | 1.86 |
E1004004 | 0.29 | 0.07 | 0.05 | 0.06 | 4.76 | |
E1009002 | 0.15 | 0.11 | 0.10 | 0.07 | 0.39 | |
E2007009 | 0.23 | 0.06 | 0.06 | 0.04 | 0.35 | |
E3002019 | 0.09 | 0.06 | 0.09 | 0.04 | 0.37 | |
E3004012 | 0.17 | 0.06 | 0.04 | 0.08 | 0.4 | |
E3006013 | 0.19 | 0.06 | 0.05 | 0.02 | 0.37 |
Subset A: five serum samples from the asthma group, showing high values of total Phadiatop sIgE levels but meanwhile 5 to 10 times lower levels of allergen mix sIgE although they were both positive by Phadiatop and previous ImmunoCAP assays; Subset B: eight serum samples from the asthma group, mono-positive to mx2 but negative by Phadiatop, with mx2 sIgE levels between 0.35 and 0.90 kUA/L, and total Phadiatop sIgE level largely between 0.10 and 0.35 kUA/L; Subset C: seven serum samples from the non-asthma group were Phadiatop-positive but tested negative for allergen mix. hx2, house dust mix; mx2, molds and yeasts mix; tx4, tree pollen mix; wx5, weed mix.