Table III.
Plasma lipid levels (mmol/l) after eight weeks of treatment.
| Plasma lipid | Statin/col (n=60) | Statin/eze (n=60) | Statin mono (n=60) |
|---|---|---|---|
| LDL-C | 1.7±0.4a | 1.9±0.3a | 2.1±0.4 |
| Total C | 3.1±0.6 | 3.3±0.4 | 3.5±0.6 |
| HDL-C | 1.3±0.3 | 1.1±0.3 | 1.2±0.3 |
| Triglycerides | 1.4±0.4 | 1.4±0.4 | 1.5±0.5 |
The plasma levels of LDL-C, total C and triglycerides were reduced by the three treatments. The plasma levels of HDL-C were increased by statin/col treatment and were reduced by statin/eze and statin monotherapy. Values are expressed as the mean ± standard deviation.
a
P<0.05 vs. the statin mono group. col, colesevelam; eze, ezetimibe; mono, monotherapy; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol.