Table I.
Serum ALT, AST, GGT activities, and total Bil in control rats and NAFL rats untreated and treated with different doses of bee venom.
| Group II (NAFL) | |||||
|---|---|---|---|---|---|
| Bee venom treated | |||||
| Parameter | Group I (control) (n=10) | Untreated (n=10) | 0.01 mg/kg (n=10) | 0.05 mg/kg (n=10) | 0.1 mg/kg (n=10) |
| ALT (U/l) | 46.6±3.40 | 67.85±8.73a | 41.85±12.11b | 40.45±9.35b | 39.65±10.00b |
| AST (U/l) | 128.2±23.65 | 204.70±32.00a | 121.20±22.80b | 122.90±10.54b | 122.60±18.55b |
| GGT (U/l) | 13.3±2.00 | 51.50±3.60a | 43.60±10.38a | 38.90±14.19a,b | 36.90±6.51a,b |
| Bil (mg/dl) | 0.54±0.30 | 1.67±0.22a | 1.04±0.18a,b | 1.14±0.21a,b | 0.93±0.12a,b |
Data expressed as mean ± SD.
a
Significantly different from control rats by ANOVA (P<0.05)
b
Significantly different from untreated NAFL rats by ANOVA (P<0.05). ALT, alanine aminotransferase; AST, aspartate aminotransferase; GGT, gamma-glutamyltransferase; Bil, bilirubin; NAFL, non-alcoholic fatty liver; ANOVA, one-way analysis of variance.