. 2018 Apr 3;15(6):5091–5099. doi: 10.3892/etm.2018.6028

Table III.

The serum and hepatic levels of glutathione system in control rats and NAFL rats untreated and treated with different doses of bee venom.

		Group II (NAFL)

			Bee venom treated

Parameter	Group I (control) (n=10)	Untreated (n=10)	0.01 mg/kg (n=10)	0.05 mg/kg (n=10)	0.1 mg/kg (n=10)
Serum tGSH (µmol/l)	83.61±5.34	64.84±8.71^a	65.09±10.57^a	69.65±16.09^a	69.37±7.37^a
Serum GSH (µmol/l)	73.95±4.84	43.58±10.85^a	49.91±8.89^a	54.74±17.64^a	56.30±9.72^a
Serum GSSG (µmol/l)	4.82±1.08	10.63±1.50^a	7.59±2.11^a,b	7.47±1.27^a,b	6.55±1.87^b
Serum GSH/GSSG	15.93±3.19	4.29±1.67^a	7.04±2.17^a	7.72±3.10^a	9.55±4.07^a,b
Hepatic tGSH (µmol/g liver)	1.92±0.20	1.03±0.27^a	1.17±0.35^a	1.27±0.50^a	1.42±0.39^a
Hepatic GSH (µmol/g liver)	1.78±0.27	0.65±0.30^a	0.89±0.35^a	1.08±0.46^a	1.14±0.41^a,b
Hepatic GSSG (µmol/g liver)	0.07±0.01	0.19±0.04^a	0.15±0.07^a	0.14±0.04^a	0.14±0.05^a
Hepatic GSH/GSSG	27.45±5.61	3.74±1.97^a	7.09±4.20^a	8.69±4.56^a	10.87±8.62^a,b

Data expressed as mean ± SD.

Significantly different from control rats by ANOVA (P<0.05)

Significantly different from untreated NAFL rats by ANOVA (P<0.05). ANOVA, one-way analysis of variance; NAFL, non-alcoholic fatty liver; GSH, reduced glutathione; tGSH, total glutathione; GSSG, glutathione disulphide.