FIG 4.
Kinetics of viral load levels in various tissues of CV-A6-infected mice at different time points. One-day-old ICR mice were intracerebrally inoculated with Changchun046 (105.0 CCID50/ml) (A), Changchun097 (104.0 CCID50/ml) (B), Changchun099 (105.0 CCID50/ml) (C), and Changchun098 (105.0 CCID50/ml) (D). The viral loads were detected by qRT-PCR at days 2, 4, and 6 postinfection in 10 samples. The results represent the mean viral loads (log10 copies per milligram of tissue or log10 copies per milliliter of blood) ± SD (3 mice/group; repeated 3 times). The data shown are representative of the results of three independent experiments.