FIG 1.

Phylogenetic analysis of ConD-HEF protein. The phylogenetic relationship of HEF amino acid sequences between consensus vaccine (ConD-HEF) and 19 IDVs isolates was illustrated in a neighbor-joining phylogeny plot (left panel) and a highlighter plot (right panel). In the phylogeny plot, the consensus HEF is depicted as a closed red circle, D/swine/Oklahoma/1334/2011 (D/OK) as an open blue circle, and D/bovine/Oklahoma/660/2013 (D/660) as an open green circle. The scale bar length represents 0.005 amino acid substitutions per site. Amino acid polymorphisms in the highlighter plot are indicated by a colored mark.