Fig. 4.

Comparison of brain GM volume in cataract patients before and after surgery. Surface maps show the changes in GM volume between preoperative and postoperative time points (at a whole-brain threshold of P < 0·01, FDR corrected, voxels > 200, repeated measures analysis of variance). Slice overlays and plots represent the mean signals from the smoothed difference images for each cluster. Significant differences in the signals are highlighted in the red circles. Blue and cyan reflect decreases. Red and yellow reflect increases, and t indicates the peak t-score value for the t-test. a, b, No significant difference in the GM volume signal was detected between the preoperative time point and the 1-week (a) or 3-month (b) postoperative time points. c, Compared with the preoperative values, the GM volumes observed at 6 months after surgery were significantly increased in the calcarine, fusiform, anterior/middle cingulate gyrus, inferior/middle frontal gyrus, inferior/medial orbitofrontal cortex, and precentral/postcentral gyrus. Notes: Mid, middle; Sup, superior; R, right; Frontal. Inf. Orb, inferior orbitofrontal cortex; Frontal. Med. Orb., medial orbitofrontal cortex.