Table 2.

Clinical parameters and 25OHVD serum levels of healthy pregnant women and preeclamptic women.

Variable	First trimester (T1)			Second trimester (T2)			Third trimester (T3)
	Healthy pregnant	Preeclamtic	P value	Healthy pregnant	Preeclamtic	P value	Healthy pregnant	Preeclamtic	P value
Age (years) median (IQR)	23 (19–30)	20 (18–26)	0.134	NA	NA	NA	NA	NA	NA
Gestational age (weeks) median (IQR)	12.1 (11–13.6)	12.3 (11.2–13.4)	0.969	24 (24.2–24.6)	24.3 (24.1–24.5)	0.434	34.5 (34.2–35.4)	34.9 (34.2–35.5)	0.395
BMI (kg/m2) mean ± s.d.	22.6 ± 2.4	22.6 ± 2.4	<0.001	24.4 ± 2.5	26.4 ± 2.8	<0.001	26.3 ± 2.3	29.4 ± 2.7	<0.001
SBP (mmHg) mean ± s.d.	95 ± 5	95 ± 5	<0.001	93 ± 10	104 ± 9	<0.001	98 ± 10	109 ± 1	<0.001
DBP (mmHg) mean ± s.d.	60 (60–64)	68 (60–70)	<0.05	60 (58–60)	63 (60–70)	<0.01	62 (60–70)	60 (60–70)	0.4045
Leptin (ng/mL) median (IQR)	20.5 (17.2–21.5)	32.6 (28.9–38.0)	<0.001	25.4 (20.2–27.3)	61.1 (51.0–77.7)	<0.001	35.1 (28.6–42.3)	87.9 (24.3–18.5)	<0.001
25-OHVD (ng/mL) mean ± s.d.	26.5 ± 5.3	28.3 ± 8.1	0.561	30.1 ± 8.1	29.6 ± 6.4	0.952	31.9 ± 8.6	29.3 ± 7.5	0.358

The non-normal variables indicated as median (IQR). The variables with normal distribution are indicated as mean ± s.d.

DBP, diastolic blood pressure, NA, non-applicable; SBP, systolic blood pressure.