Figure 2.

FEF inactivation decreased preparatory activity in the ipsilesional iSC. A–C, Spike rasters (below) and mean spike density functions (above, mean ± SE) showing reduced (A, B) or unchanged preparatory activity (C) during FEF inactivation. Inset shows the magnified view of the relevant period of interest. Box plots show the SRT changes for the corresponding behavioral sessions (median, 25–75th percentile and the range). All the sessions showed significant increases in SRT (p < 0.05, Wilcoxon rank sum test). Pre- and post-cooling trials pooled as FEFwarm (red), and trials during FEF inactivation are shown as FEFcool (blue). Across all the neurons (n = 35), FEF inactivation did not alter baseline activity (D) but reduced PREP activity (E), the slope of PREP activity (F), and the final level of PREP activity (G) at a p value level of 0.05 (Wilcoxon sign rank test). Circles and squares represent data from monkey DZ and OZ, respectively; filled symbols represents significant change at individual neuron level.